и еще - у меня реактиващия зостера была.. может перекрест? я в английском мало что понимаю.. с переводчиком нашла вот такой текст
Criticism is often based on the frequency of false-positive results of the Borrelia-LTT (5). This problem continues to exist unless there is sufficient testing of the antigen specificity of the Borrelia-LTT. In the case of frequently false positive reactions, the dose of the test antigens is too high. Currently, since there is no available gold standard for the laboratory diagnosis of borreliosis or its exclusion, the Borrelia-LTT can only be validated according to clinical and serological findings. Nevertheless, there are still gaps in the validation that we conducted. For instance, it was only possible in individual cases to examine patients with active syphilis (n = 3) or leptospirosis infection (n = 2) for potential cross reactivity. In these few cases, there was no evidence of such cross-reactivity in the Borrelia-LTT. Allergies, autoimmune diseases and acute, persistent and latent viral infections (including HIV, EBV, CMV, VZV) have now been excluded, by further investigations, as a possible cause of false-positive reactions (unpublished data).
ссылка Suppl 1: The Lymphocyte Transformation Test for Borrelia Detects Active Lyme Borreliosis and Verifies Effective Antibiotic Treatment
Criticism is often based on the frequency of false-positive results of the Borrelia-LTT (5). This problem continues to exist unless there is sufficient testing of the antigen specificity of the Borrelia-LTT. In the case of frequently false positive reactions, the dose of the test antigens is too high. Currently, since there is no available gold standard for the laboratory diagnosis of borreliosis or its exclusion, the Borrelia-LTT can only be validated according to clinical and serological findings. Nevertheless, there are still gaps in the validation that we conducted. For instance, it was only possible in individual cases to examine patients with active syphilis (n = 3) or leptospirosis infection (n = 2) for potential cross reactivity. In these few cases, there was no evidence of such cross-reactivity in the Borrelia-LTT. Allergies, autoimmune diseases and acute, persistent and latent viral infections (including HIV, EBV, CMV, VZV) have now been excluded, by further investigations, as a possible cause of false-positive reactions (unpublished data).
ссылка Suppl 1: The Lymphocyte Transformation Test for Borrelia Detects Active Lyme Borreliosis and Verifies Effective Antibiotic Treatment
